Personalized medicine: Right drug, right patient, right timeThe premise is to use a patient’s own genetic information to guide decisions for prevention, diagnosis, and treatment of disease and other health conditions.
In this issue
Pediatric high-grade glioma is not one tumor type but manyStratifying tumors by their clinical characteristics and underlying biology will enable future targeting of specific therapies for glioma in children. Treatment investigated to prevent blood-clotting disorders November 01, 2017By Rachael Zimlich RNA new subcutaneous therapy could offer a promising solution to a bleeding disorder in both children and adults. Two potential drugs to treat Dravet syndromePhase III clinical trials of new antiepileptic medications show promise for reducing frequency of convulsive seizures in children.
Growth-accommodating implants could repair heart valve defectsA new device for the heart is designed to accommodate a child’s growth, potentially improving the success rate of a valve repair and reducing the need for more operations.
Noninvasive imaging monitors early human brain developmentNew research looks at the role of maternal-placental-fetal interaction on cognitive function and disease.
Personalized and costly, but new ALL treatment offers hope November 01, 2017By Rachael Zimlich RNA new customized therapy for acute lymphoblastic leukemia (ALL) offers high remission rates but at a substantial cost, and only at specialized cancer centers.
Ears, nose, and throat, oh, my!From ear infections to croup to strep, I have found that the simplest diagnosis is often the best diagnosis.
ACEs: Caught in the cross fire November 01, 2017By Brian R. Stork MDA physician’s curiosity leads to discovery of both the cause and a “cure” for the effects of adverse childhood experiences (ACEs) on patient health.
Infant girl develops bulging sacral massA 3-week-old female presented to the emergency department with a 3-day history of a progressively enlarging, erythematous, seemingly painful lump on her back.
Teenaged girl distressed by persistent rashA 16-year-old girl presents for evaluation of an asymptomatic brown rash over her central chest and back that developed over the preceding 6 months. She is embarrassed by the appearance.
M pneumoniae infection hits preschoolers hardA study of Mycoplasma pneumoniae disease during an epidemic in Norway found that preschool children infected with this bacterium had a significantly higher risk of severe disease, particularly severe pneumonia, than school-aged children.
An app for assessing neonatal jaundice? You bet!A study of the accuracy of a technology for assessing jaundice in outpatient neonates based on analysis of digital images demonstrated that this smartphone application (app) may be useful for screening newborns for jaundice. Hospitalized preterm infants benefit from mothers’ recorded voicesBeing exposed to recordings of their mothers’ voices limited pain preterm infants experienced while undergoing heel lance procedures, according to a study conducted in an Italian neonatal intensive care unit.