HPS develops in premature infants later than in term infants
Hypertrophic pyloric stenosis (HPS) develops in premature infants later than in term infants. A study in 217 premature infants with HPS showed that premature infants are likely to present with HPS at an older age than are term infants with this condition. Further, the greater the degree of prematurity, the older the chronologic age at presentation. Overall, HPS manifested in premature infants at a median age of 5.3 weeks and had a peak incidence at 44 to 50 weeks postconception (Costanzo CM, et al. Clin Pediatr (Phila). 2017;56:127-131).