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Journal Club

Limiting duration of antibiotics in OM limits their effectivenessTreating children with acute otitis media with amoxicillin-clavulanate for 5 days is less effective than following standard 10-day treatment, according to a study in 520 such children who were aged 6 to 23 months.
Concentration matters in newer urinalysis techniquesIn a retrospective study of 27,000 infants aged younger than 3 months evaluated for urinary tract infection (UTI) with paired urinalysis and urine culture, investigators set out to determine the optimal urine white blood cell (WBC) threshold for UTI when using an automated urinalysis system stratified by urine concentration.
Overweight is not treated in children hospitalized with asthmaA retrospective record review for youngsters admitted with asthma to a Midwestern children’s hospital revealed that overweight and obesity were underrecognized, underdiagnosed, and undertreated.
Medication or placebo to prevent migraine?A trial comparing amitriptyline, topiramate, and placebo for prevention of migraine in children and adolescents with a history of migraine found that all 3 had about the same effect on reducing headache frequency or headache-related disability.
Effective early autism intervention has long-term impactA follow-up trial conducted 6 years after the conclusion of a randomized controlled trial of early intervention in autism spectrum disorder demonstrated that the intervention had a long-term effect on autism symptoms and continued effects on parent and child social interaction.
More time spent standing in school reduces BMIChildren who spent 2 consecutive years in classrooms outfitted with desks at which they worked standing (or while sitting on a stool) had a significantly lower body mass index (BMI) than their peers in classrooms with traditional standard desks, a recent study reported.
Why aren’t pediatricians recommending HPV vaccination more strongly?In a recently published essay to address this question, the authors suggest that pediatricians may present human papillomavirus (HPV) vaccine as optional or less urgent than other adolescent vaccines because they do not often read or hear about their patients’ being affected by HPV-associated cancers, which generally strike older populations.
Does a tax on sugar-sweetened beverages work?A study conducted in Berkeley, California, the first US jurisdiction to implement an excise tax on sugar-sweetened beverages (SSBs), found that consumption of SSBs decreased 21% in that city after the tax was imposed.
Oral syringes dose more accurately than cupsParents are less likely to make dosing errors when giving their child liquid medications if they use an oral syringe--rather than a cup-- to measure the dose, a recent trial showed.
Do LABAs given with glucocorticoids increase severe asthma events?Results of a randomized trial in children with asthma comparing concomitant use of the inhaled glucocorticoid fluticasone propionate plus the long-acting beta-agonist (LABA) salmeterol with use of fluticasone alone indicate that the answer to this question is “no.”

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