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Journal Club

FDA’s youth antismoking campaign boasts good resultsExposure to the US Food and Drug Administration (FDA) youth-specific national antismoking media campaign—The Real Cost—was associated with preventing young persons from beginning to smoke.
Age-restricted supplements sold to male teensSales associates at health food stores, which primarily sell dietary supplements, often recommend creatine products and, sometimes, testosterone boosters to young teenaged boys, according to a study involving 244 stores in 49 states.
Crizanlizumab helps prevent pain crises in sickle cell diseaseIn patients with sickle cell disease, therapy with crizanlizumab, an antibody against the adhesion molecule P-selectin, resulted in a significantly lower rate of sickle cell-related pain crises than placebo, a trial in 198 patients aged from 16 to 65 years showed.
HPS develops in premature infants later than in term infantsA study in 217 premature infants with HPS showed that premature infants are likely to present with HPS at an older age than are term infants with this condition.
LCPUFAs in pregnancy lower child’s asthma riskWomen in the third trimester of pregnancy who take supplements of n-3 long-chain polyunsaturated fatty acids (LCPUFAs) reduce their children’s risk of persistent wheeze or asthma as well as of lower respiratory tract infections, a study in Denmark demonstrated.
Meningococcal vaccine might raise risk of Bell’s palsyIn a study of almost 48,900 vaccinated individuals, investigators observed a temporal association between development of Bell’s palsy and administration of quadrivalent meningococcal conjugate vaccine (MCV4) that protects against serogroups A,C, Y, and W (MenACWY) when the vaccine was given at the same time as other vaccines.
Two-step egg introduction helps prevent egg allergyStepwise introduction of egg (starting with a low dose, which is then increased), along with aggressive treatment of atopic dermatitis (AD), is a safe and effective way to prevent hen’s egg allergy in high-risk infants, a study in Japan showed.
Hitting kids is linked to aggressive behaviorAn interview-based study conducted in 372 parents visiting pediatric emergency departments with children aged younger than 4 years found that parents who used physical discipline were 2.8 times more likely than parents who did not use this form of discipline to report that their children engage in hitting, kicking, and throwing.
Top 10 studies you may have missed- 2017It’s that time again! Here are Dr Michael Burke’s favorite 10 articles he reviewed in Journal Club for Contemporary Pediatrics during the past 12 months that are most likely to change your practice, improve patient care, or illuminate future trends in pediatrics.
How best to reduce injection pain—lidocaine creamA comparison of 4 levels of pain management of routine vaccine injections found that of the remedies tried, only liposomal lidocaine applied at the injection site provided consistent relief.

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