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Michael G Burke, MD
Gene variants relate to risk of respiratory infections and AOM
Certain polymorphisms in mannose-binding lectin (MBL) and toll-like receptors (TLRs), genes that have a role in the innate immune system, promote susceptibility to or protection against respiratory and rhinovirus infections and acute otitis media (AOM), according to a study in Finnish infants.
Does residential ‘greenspace’ help asthma control?
A study in 150 asthmatic children (aged 9 to 17 years) found an interaction between family relationships and residential greenspace, suggesting that children with asthma benefit when they live in high greenspace areas and have positive family relationships.
Families detect errors hospital incident reports miss
Rates of medical errors yielded by solicited family reporting were 5 times higher than the rates provided by hospital incident reports and the rates of adverse events (AEs) were 3 times higher, a study in 4 pediatric hospitals found. Most hospitals primarily use incident reports to conduct patient safety surveillance.
Poor housing is associated with asthma morbidity
A new study found that the well-documented racial/ethnic disparities in asthma diagnosis and morbidity are diminished after accounting for material hardship.
Consumers buy fewer cigarettes after CVS stops selling them
After CVS, the large retail pharmacy chain, stopped selling cigarettes in its stores, many consumers who used to buy their smokes at CVS simply bought fewer cigarettes and presumably smoked less.
ICS often does not follow asthma hospitalization
Fewer than half of commercially insured children who have been hospitalized for asthma receive an inhaled corticosteroid (ICS), even though many of them make outpatient visits within 30 days of hospital discharge.
Crizanlizumab helps prevent pain crises in sickle cell disease
In patients with sickle cell disease, therapy with crizanlizumab, an antibody against the adhesion molecule P-selectin, resulted in a significantly lower rate of sickle cell-related pain crises than placebo, a trial in 198 patients aged from 16 to 65 years showed.
Age-restricted supplements sold to male teens
Sales associates at health food stores, which primarily sell dietary supplements, often recommend creatine products and, sometimes, testosterone boosters to young teenaged boys, according to a study involving 244 stores in 49 states.
FDA’s youth antismoking campaign boasts good results
Exposure to the US Food and Drug Administration (FDA) youth-specific national antismoking media campaign—The Real Cost—was associated with preventing young persons from beginning to smoke.
LCPUFAs in pregnancy lower child’s asthma risk
Women in the third trimester of pregnancy who take supplements of n-3 long-chain polyunsaturated fatty acids (LCPUFAs) reduce their children’s risk of persistent wheeze or asthma as well as of lower respiratory tract infections, a study in Denmark demonstrated.

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