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Cheryl Guttman Krader
Algorithm could change way to treat wet AMD
An algorithm for guiding clinical judgments about the futility of anti-VEGF treatment of neovascular age-related macular degeneration (nvAMD) has importance from clinical, ethical, and legal perspectives and would be a valuable decision-making tool for retina specialists and payors, according to David T. Wong, MD.
Multiple strategies pursue treatment of dry AMD
There are a number of ongoing clinical trials investigating treatments for dry age-related macular degeneration (AMD). These modalities include medications that are already in use for other indications and investigational agents representing various novel mechanisms of action.
Case of profound posterior pressure
While participating in an ORBIS Flying Eye Hospital program in Trujillo, Peru, and operating on an elderly patient with a dense cataract under peribulbar anesthesia, James Lehmann, MD, encountered iris prolapse as soon as he made the paracentesis.
SAKURA program reinforces efficacy, safety of intravitreal sirolimus
Results from the Study Assessing double-masKed Uveitis tREAtrement (SAKURA) program support the efficacy and safety of intravitreal sirolimus 440 mcg (Opsiria, Santen) for treating noninfectious uveitis of the posterior segment, said Pauline T. Merrill, MD.
Growing attention turns to cerebrospinal fluid pressure in glaucoma
Recently, evidence has been accumulating to support the theory that cerebrospinal fluid pressure (CSFp) is also important in primary open-angle glaucoma (POAG) and normal-tension glaucoma (NTG), and the relationship has potential implications for clinical practice, said R. Rand Allingham, MD.
ILM removal increases ease, safety of subretinal injections
Removing a small area of internal limiting membrane at the intended site of a subretinal injection allows the injection to be delivered without penetrating the retina.
Melanoma staging updates
The American Joint Committee on Cancer (AJCC) 8th Edition Melanoma Staging System includes important changes pertaining to T1 melanomas. The role of sentinel lymph node biopsy (SLNB) continues to evolve, particularly for thin melanomas. A contemporary international dataset is being applied to develop sophisticated and accurate personalized prognostic tools.
Does FLACS cost, benefit outweigh manual? Yes!
Though further study is needed to determine conclusively whether or not femtosecond laser-assisted cataract surgery (FLACS) is associated with better refractive outcomes compared with conventional manual surgery, FLACS offers many other benefits that justify its use, according to Robert J. Cionni, MD.
Does FLACS cost, benefit outweigh manual? No!
Femtosecond laser-assisted cataract surgery (FLACS) offers some advantages compared with a conventional manual procedure, particularly for certain patients. Currently, however, FLACS does not result in superior outcomes and it has drawbacks that outweigh its benefits, according to Rosa Braga-Mele, MD.
Redesigned pupil expansion device reduces cataract surgery risks
Pre-treatment with the femtosecond laser in eyes undergoing cataract surgery can induce miosis. The use of a pupil expansion device, however, offers an effective method for managing small pupils in femtosecond laser-assisted cases whether the problem pre-exists or is caused by the laser, said Boris Malyugin, MD, PhD.

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